American Society of Microbiology ABMM - ABMM
- Exam Code: ABMM
- Exam Name: ABMM
- Updated: Jul 29, 2026
- Q & A: 204 Questions and Answers
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| Section | Objectives |
|---|---|
| Clinical Microbiology | - Bacteriology
|
| Laboratory Management & Quality Systems | - Quality assurance and quality control
|
| Infectious Disease Principles | - Epidemiology
|
| Laboratory Operations | - Diagnostic workflow
|
1. A patient with severe combined immunodeficiency (SCID) develops a progressive respiratory illness.
Bronchoalveolar lavage fluid is examined using direct fluorescent antibody (DFA) staining, which reveals numerous cysts of Pneumocystis jirovecii. The cysts appear:
A) Large and multinucleated with prominent endospores.
B) Oval-shaped with a thin wall and internal nuclei.
C) Cup-shaped or helmet-shaped with internal structures.
D) Small and round with a thick wall, containing sporozoites.
2. A patient with cystic fibrosis experiences a pulmonary exacerbation. Sputum culture grows a mucoid strain of Pseudomonas aeruginosa. The mucoid phenotype is primarily due to the overproduction of:
A) Exotoxin A
B) Alginate
C) Pyocyanin
D) Elastase
3. A 6-year-old child presents with a pharyngitis characterized by a grayish-white pseudomembrane covering the tonsils and posterior pharynx. Gram stain of the membrane reveals Gram-positive bacilli. Culture on Loeffler's medium shows growth of metachromatic granules. The MOST significant virulence factor associated with this organism's pathogenicity is:
A) Protein A
B) Diphtheria toxin
C) Hyaluronidase
D) Streptolysin O
4. Clavulanic acid is often combined with amoxicillin (e.g., Augmentin™) to overcome certain types of bacterial resistance. What is the primary mechanism by which clavulanic acid enhances amoxicillin's activity?
A) It inhibits bacterial efflux pumps that would otherwise remove amoxicillin from the cell.
B) It increases the outer membrane permeability to amoxicillin in Gram-negative bacteria.
C) It functions as a potent, irreversible inhibitor of many bacterial beta-lactamase enzymes.
D) It binds to alternative penicillin-binding proteins (PBPs), providing a synergistic bactericidal effect.
5. A patient with a history of valvular heart disease undergoes a dental procedure and subsequently develops a bloodstream infection with Streptococcus mutans. This organism gains access to the bloodstream primarily due to:
A) Active invasion of the oral mucosa.
B) Transient bacteremia resulting from the procedure.
C) Formation of a protective biofilm on the teeth.
D) Production of potent extracellular enzymes.
Solutions:
| Question # 1 Answer: C | Question # 2 Answer: B | Question # 3 Answer: B | Question # 4 Answer: C | Question # 5 Answer: B |
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